Steven’s bump is so large, his daughter thinks he is growing a monster on his back. Catherine’s arm lump has grown so big that it’s nearly up to her armpit….

Elaine calls the growth on her love handle her third breast. Jessica’s cyst is close to her eye and could be dangerous for Dr. Lee to remove. Dwayne wants his…

Bob suffers from mysterious open-wound sores all over his body. Virginia’s stress-ball-sized lump is such a pain in her neck that she can’t wait to have it removed. Ted suffers…

John lost his sight at a young age and soon after began growing lumps on his body. Lynette has hundreds of pebble-sized bumps all over her arms, chest and belly….

Robert has thousands of unique bumps on his arms that Dr. Lee has never seen. Alexis has a painful cheek cyst that oozes and has a pungent odour. Stuart’s cluster…

Casey’s birthmark covers most of her face, head and neck. James has mysterious massive growths on his inner thigh and lower abdomen that are completely puzzling. Jerry had to hang…

Elizabeth’s head is covered with giant cauliflower-shaped bumps. Jamaal has been growing a strange knob on the left side of his butt since he was just a boy. Donna’s cracking,…

Dr. Lee faces off with iguana-wrangler Madison’s head growths. Chanel suffers from painful cyst tunnels beneath her armpit skin that leak and smell like the food she eats. The dark…

Johnnie’s crippling psoriasis keeps him from spending time with his daughter. Aimee has a Mohawk of cysts on her head. Edith’s face markings and itchy skin condition turn out to…

Eric hopes Dr. Lee is able to remove the giant growth from his behind. Breanna suffers from itchy dry skin she can’t help but scratch. Michael makes jokes, but he…

Debra has a large, brainlike growth on the side of her head that feels like a sponge, has crevices and emits an odor. Dusten is a cowboy looking to remove…

Robert is back to see if Dr. Lee and Dr. Umar can remove his recurring head keloid for good. Justice has small lesions all over her body that get inflamed….

Robert is back to see if Dr. Lee and Dr. Umar can remove his recurring head keloid for good. Justice has small lesions all over her body that get inflamed….

Robert is back to see if Dr. Lee and Dr. Umar can remove his recurring head keloid for good. Justice has small lesions all over her body that get inflamed….

Robert has a small keloid on his ear and a large, snakelike keloid on the back of his head that has been removed and returned three times. Angela has four…

Robert has a small keloid on his ear and a large, snakelike keloid on the back of his head that has been removed and returned three times. Angela has four…

Robert has a small keloid on his ear and a large, snakelike keloid on the back of his head that has been removed and returned three times. Angela has four…

Roger has a considerable growth on his shoulder that he calls his “second head.” Jenna is a bubbly teenager with an even bigger bubble behind her ear. Susan is covered…

Dermatologist Sandra Lee, aka Dr. Pimple Popper, helps patients with unique skin conditions reclaim a life free of disguise and embarrassment.

Margarita is a matriarch who has been hiding her armpit lump from her family; Kayla is an aspiring musician with a promising career that her painful eczema has brought to…

Jeremy is a pastor with a hanging growth in an embarrassing location. Evelyn has recurring keloids that have been removed three times and come back bigger each time. Todd has…

Tameru is a drag queen, but he has a myriad of cysts that are the real drag. Devon has uneven skin she thinks may be the result of a hysterectomy…

Jason has lost confidence and motivation due to the large growth on his neck. Shawnell has multiple mystery bumps on her head that have destroyed her self-esteem. Jim has a…

Gabriel has a huge growth on his clavicle but is terrified of surgery. Karen has dealt with painful, scaly feet for 22 years with no diagnosis. Lorne has embarrassing tumors…

Ruben is a personal trainer whose head growth has prevented him from seeing clients. Kaitlin has blue marks and scars up and down her arms due to long-term drug use….

Jaclyn has a lump on the back of her head that causes her emotional distress. Shane has a growth between his eyes that could put him in danger at his…

Keke is covered in bumps that make her embarrassed to be intimate with her husband. Jim is a widower with two lumps who wants them removed for himself and his…

Stacey’s shoulder growth prevents her from being the playful teacher she once was. Matthew worries that his mysterious shin rash may be dangerous. Both need Dr Pimple Popper’s help to…

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches; Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort; Sharon…

Terry’s nose growth has prevented him from meeting his grandkids; Remi has alligator-like skin and is not used to taking care of herself; Austin has an embarrassing birthmark right next…

Roger returns with his gigantic nose growths in the hopes that Dr. Lee and her colleagues can help before it’s too late. Christine has lost her essence due to a…

Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps. Leonardo has a fist-size growth on his head, but he is terrified of doctors. Tamyra…

Monica returns for a second time in the hopes that Dr. Lee can remove some more of her face growths. Ken has several large cysts on his head that he…

Corey is a drag queen and has a bump dangling from his booty; Adam has a semi-circle of about a dozen cysts on his head that he covers with a…

Roger has enormous growths on his nose that drip pus, attract flies, and are so large that he can barely breathe; Sandra and Jessie are sisters who bonded over their…

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain;…

Stephen’s large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has…

John fears the large lump on his neck could become so big that it may eventually suffocate him. Shoshana is depressed because of the big growth on her forehead. Ashley…

Yaellie, a sweet 9-year-old, has itchy psoriasis on over 90 percent of her body. Matt, a former Marine, has a large recurring lump in his armpit. Twins Tracie and Stacie…

Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft…