Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: David Letterman.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Amy Poehler.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Gabrielle Union.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Ava DuVernay.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guests: Spike Lee and Matt Walsh.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Lil Nas X, and a special appearance by Paul Scheer.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Charlize Theron.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guests: Wu-Tang Clan.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more. Illustrious guest: Bill Hader.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest: Issa Rae.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Stacey Abrams and Anna Kendrick.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest Sen. Cory Booker (D-NJ).

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest: Seth Rogen.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Ben Stiller and 2 Chainz.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Lupita Nyong’o, Winston Duke & Sen. Kirsten Gillibrand (D-NY).

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Carmelo Anthony and Jordan Peele.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest: fellow Bronx native Congresswoman Alexandria Ocasio-Cortez. Series premiere.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guest: Don Cheadle.

Desus Nice and The Kid Mero sound off on pop culture, politics, sports and more; illustrious guests: Vince Staples and John Legend.

The first ever weekly late-night talk show on Showtime features popular TV and podcast personalities Desus and Mero speaking off the cuff and chatting with guests at the intersection of…

Steven Ogg, Desus Nice and Lisa Edelstein discuss Episode 5, “The Big Scary U.”